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. 2007 Aug 28;98(11):1666–1677. doi: 10.1111/j.1349-7006.2007.00584.x

Figure 4.

Figure 4

Expression of four tetraspanin antigens during B‐cell maturation. The relative levels of expression of four tetraspanins (CD9, CD37, CD53 and CD81) are shown along the maturation pathway of normal human B cells. Red indicates maximum expression; orange indicates medium levels of expression; green indicates negativity. Expression of other maturation markers is also included. Based on Barrena et al.( 132 ) LN, lymph node; PB, peripheral blood; PC, plasma cells. The horizontal arrows indicate the B‐cell maturation pathway. The black vertical arrows indicate the two main tetraspanin switchs.