Table 1.

Proteins that interact with tetraspanins

	CD9	CD53	CD81	CD82	CD151	CD63	CD37
α3β1	+	+	+	+	+	+	+
α4β1	+	+	+	+	ND	+	ND
α6β1	+	+	+	+	+	+	ND
α5β1	+	ND	+	+	ND	+	ND
Precursor β1	+	ND	–	–	ND	–	ND
αIIbβ3	+	ND	ND	ND	ND	ND	ND
α6β4	–	ND	–	ND	+	–	ND
CD11/CD18	ND	ND	ND	ND	ND	+	ND
HLA‐DR	ND	+	+	+	ND	+	+
HLA‐DM	ND	ND	ND	+	ND	+	ND
HLA‐DQ	ND	+	+	+	ND	ND	ND
HLA‐DO	ND	ND	ND	+	ND	+	ND
EGF‐R	ND	ND	ND	+	ND	ND	ND
TGF‐α	+	ND	ND	ND	ND	ND	ND
FGFR	+	ND	+	ND	ND	ND	ND
c‐Met	+	ND	ND	+	ND	ND	ND
HB‐EGF	+	ND	–?	–?	ND	ND	ND
FRPP	+	ND	+	ND	ND	ND	ND
EWI‐2	+	ND	+	+	ND	ND	ND
EWI‐F	ND	ND	+	ND	ND	ND	ND
CD36	+	ND	ND	ND	ND	ND	ND
CD9P‐1	+	ND	+	+	+	+	ND
CD2	ND	+	ND	ND	ND	ND	ND
CD4	ND	ND	+	+	ND	ND	ND
CD8	ND	ND	+	+	ND	ND	ND
CD21‐CD19‐Leu13	ND	ND	+	ND	ND	ND	ND
CD19	+	ND	+	+	ND	ND	ND
CD20	ND	+	+	+	ND	ND	ND
CD46	+	ND	+	+	+	ND	ND
Protein kinase C	+	+	+	+	+	–	–
Phosphatidylinositol 4‐kinase	+	–	+	–	+	+	ND
Dectin‐1	ND	ND	ND	ND	ND	ND	+
Syntenin 1	ND	ND	ND	ND	ND	+	ND
γ‐Glutamyl transpeptidase	ND	+	+	+	ND	ND	ND

Green (+), positive interaction; red (–), no interaction; EGF‐R, epidermal growth factor receptor; EWI, Ewing; FGFR, fibroblast growth factor receptor; FRPP, prostaglandin F₂α receptor regulatory protein; HB‐EGF, heparin‐binding epidermal growth factor; HLA, human leukocyte antigen; ND, not determined; TGF, transforming growth factor.