Figure 2.

Mutations and aberrant expression of interferon regulatory factor (IRF) genes in human cancers. (a) Schematic representation of human chromosomes and gene loci of IRF genes. (b) Summary table of previous reports about mutations and aberrant expression of the IRF genes in primary specimens derived from human malignancies. Expression levels included are based on both mRNA and protein levels. AML, acute myelogenous leukemia; ALL, acute lymphocytic leukemia; CML, chronic myelogenous leukemia; NSCLC, non‐small cell lung cancer; CNS, central nervous system; t‐AML, therapy‐related acute myelogenous leukemia.