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Hematological toxicities during the first cycle of treatment with E7070
| Toxicity | Grade | Dose (mg/m2) | ||||
|---|---|---|---|---|---|---|
| 400 (n = 3) | 600 (n = 3) | 700 (n = 6) | 800 (n = 6) | 900 (n = 3) | ||
| Neutropenia | 1/2 | 0 | 0 | 3 | 1 | 0 |
| 3/4 | 0 | 2 | 0 | 3 | 3 | |
| Leukopenia | 1/2 | 1 | 2 | 3 | 3 | 1 |
| 3/4 | 0 | 0 | 0 | 2 | 2 | |
| Thrombocytopenia | 1/2 | 0 | 2 | 1 | 2 | 0 |
| 3/4 | 0 | 0 | 0 | 1 | 3 | |
| Anemia | 1/2 | 1 | 2 | 4 | 2 | 2 |
| 3/4 | 0 | 0 | 0 | 1 | 1 | |
