Table 1.

 Dose of each drug in each group

Treatment group	Drug	Day 1	Days 2–3	Days 4–5
Aprepitant 125/80 mg regimen	Aprepitant (po)	125 mg	80 mg	80 mg
	Dexamethasone (i.v.)	6 mg	4 mg	–
	Granisetron (i.v.)	40 μg/kg	–	–
Aprepitant 40/25 mg regimen	Aprepitant (po)	40 mg	25 mg	25 mg
	Dexamethasone (i.v.)	8 mg	6 mg	–
	Granisetron (i.v.)	4l0 μg/kg	–	–
Standard therapy	Aprepitant (po)	Placebo	Placebo	Placebo
	Dexamethasone (i.v.)	12 mg	8 mg	–
	Granisetron (i.v.)	40 μg/kg	–	–

i.v., intravenous; po, per os.