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Effects of mutations of Sp1-II and the novel protected site on basal and T-antigen-induced transcriptional activity in U87MG and HeLa cells. Cotransfection was performed as described for Fig. 3. (A) Comparison of nucleotide sequences of the wild-type (wt) and mutated constructs of Sp1-II and novel sites. (B) Effects of mutations on the basal and T-antigen-induced transcriptional activity in U87MG and HeLa cells.
