Table 2.
Correlations between serum levels of UA, sMICA, sMICB or cancer antigen 19‐9 (CA19‐9) and clinicopathological characteristics of PDAC
| UA | sMICA | sMICB | CA19‐9 | |
|---|---|---|---|---|
| γs (P‐value) | γs (P‐value) | γs (P‐value) | γs (P‐value) | |
| Gender | −0.322(0.001) | −0.090 (0.351) | −0.183 (0.111) | −0.078 (0.408) |
| Age | −0.053 (0.575) | 0.128 (0.190) | 0.073 (0.530) | 0.155 (0.098) |
| Size† | −0.042 (0.776) | 0.192 (0.201) | 0.562 (0.045) | 0.381 (0.007) |
| Unresectability‡ | −0.066 (0.656) | 0.074 (0.604) | 0.627 (0.022) | 0.300 (0.036) |
| Node metastasis | −0.010 (0.945) | 0.073 (0.610) | −0.134 (0.663) | 0.337 (0.018) |
| Distant metastasis | −0.130 (0.380) | 0.323 (0.021) | 0.454 (0.119) | 0.491 (0.001) |
†Analyzed by being divided into three groups according to size as follows: <2 cm; >2 cm and <5 cm; >5 cm. ‡Analyzed by being divided into resectable and unresectable; resectable was defined as tumor extending beyond the pancreas but without involvement of the celiac axis or the superior mesenteric artery (T1‐3, N0‐1, M0, stage I–II), and unresectable was defined as tumor invading the celiac axis or the superior mesenteric artery and extending into distant organs (T4, N0‐1, M0‐1, stage III–IV). γs, Spearman correlation coefficient; PDAC, pancreatic ductal adenocarcinoma; sMICA, soluble MHC class I chain‐related molecules A; sMICB, soluble MHC class I chain‐related molecules B; UA, uric acid. Values in bold font are statistically significant.