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. 2008 Mar 28;99(4):738–746. doi: 10.1111/j.1349-7006.2008.00743.x

Figure 3.

Figure 3

Knockdown of enhancer of zeste homolog 2 (EZH2) restores E‐cadherin expression and induces the membranous translocation of β‐catenin from the nucleus. (a) The re‐expression of E‐cadherin was also detected by Western blot analysis, without changing β‐catenin expression after EZH2 knockdown. (b) Human gastric cancer MKN1 cells transfected with EZH2 short interfering RNA (siRNA) show the restoration and membranous distribution of E‐cadherin (E‐cadherin, red; EZH2, green). (c) MKN1 cells transfected with EZH2 siRNA showed the translocation of β‐catenin from the nucleus to the membrane (β‐catenin, red; EZH2, green).