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Inhibitory effects of coenzyme Q (CoQ) on human DNA topoisomerase (topo) II. pUC19 supercoiled plasmid DNA was mixed with the enzyme and inhibitor. Lanes 3–7, 100 µM of CoQ1, CoQ2, CoQ4, CoQ6 and CoQ10, respectively; lanes 2–7, 0.05 units of topo II; lane 1, no enzyme. Plasmid DNA (0.25 µg) was added in each of the lanes. A photograph of the ethidium bromide‐stained gel is shown.
