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Table 3.

Inhibitory effect of coenzyme Q on the proliferation of human cancer cells

Compound LD50 values (µM)
Coenzyme Q1 14.0 1.2
Coenzyme Q2 56.5 1.8
Coenzyme Q4 168 2.5
Coenzyme Q6 >200
Coenzyme Q10 ≥200

Human promyelocytic leukemia cells, HL‐60, were incubated for 24 h and then assayed with 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl tetrazolium bromide.( 27 ) Data are expressed as the mean SD (n = 5). LD50, 50% lethal dose.