Table 2.
Genes that are up‐regulated in LNMLECs
| UniGene ID | Gene symbol | Gene function | Cytoband | SLR |
|---|---|---|---|---|
| Hs.525607 | TNFAIP2 | Angiogenesis | chr14q32 | 1.6 |
| Hs.468675 | PDPN | Lymphangiogenesis | chr1p36.21 | 1.1 |
| Hs.515126 | ICAM1 | Cell–cell adhesion | chr19p13.3 | 1.1 |
| Hs.434971 | TRO | Cell adhesion | chrXp11.22 | 3.4 |
| Hs.570065 | COL4A3 | Cell adhesion | chr2q36 | 3.9 |
| Hs.436657 | CLU | Apoptosis | chr8p21 | 1.9 |
| Hs.591785 | IER3 | Apoptosis | chr6p21.3 | 1 |
| Hs.514913 | SERPINB2 | Anti‐apoptosis | chr18q21.3 | 4.1 |
| Hs.271955 | TNFAIP8 | Anti‐apoptosis | chr5q23.1 | 1 |
| Hs.134830 | COL8A1 | Cell adhesion | chr3q12.3 | 1 |
| Hs.567276 | GPC3 | Morphogenesis | chrXq26.1 | 4 |
| Hs.590919 | ADAMTS3 | Collagen catabolism | chr4q13.3 | 1.8 |
| Hs.382202 | CHI3L1 | Arbohydrate metabolism | chr1q32.1 | 5.7 |
| Hs.34012 | BRCA2 | Regulation of progression | chr13q12.3 | 1 |
| Hs.128518 | EFNA5 | Cell–cell signaling | chr5q21 | 1.2 |
| Hs.303649 | CCL2 | Chemotaxis | chr17q11.2 | 2.8 |
| Hs.75498 | CCL20 | Chemotaxis | chr2q33 | 3.1 |
| Hs.251526 | CCL7 | Chemotaxis | chr17q11.2 | 2.5 |
| Hs.789 | CXCL1 | Chemotaxis | chr4q21 | 4.2 |
| Hs.590921 | CXCL2 | Chemotaxis | chr4q21 | 4.3 |
| Hs.89690 | CXCL3 | Chemotaxis | chr4q21 | 4.3 |
| Hs.89714 | CXCL5 | Chemotaxis | chr4q12‐q13 | 4.3 |
| Hs.164021 | CXCL6 | Chemotaxis | chr4q21 | 4 |
Gene symbols and descriptions are derived from the NCBI UniGene database. Expression ratios refer to LNMTca8113‐stimulated lymphatic endothelial cells (LNMLECs) versus Tca8113‐stimulated LECs (TLECs). Function is derived from the SOURCE database and published literature. SLR, signal log ratio.