Table 5.
Prognostic factors of stage IV marginal zone B‐cell lymphoma
| TTP | OS | |||
|---|---|---|---|---|
| P‐value* | Hazard ratio (95% CI) | P‐value* | Hazard ratio (95% CI) | |
| Age ≥60 | 0.227 | 1.398 (0.812–2.406) | 0.607 | 1.388 (0.398–4.833) |
| Gender : male | 0.583 | 0.853 (0.483–1.505) | 0.896 | 1.088 (0.306–3.866) |
| PS (ECOG) ≥ 2 | 0.722 | 1.183 (0.469–2.983) | 0.546 | 0.044 (0.000–1112.6) |
| LDH > Normal | 0.252 | 1.391 (0.791–2.446) | 0.571 | 1.497 (0.371–6.030) |
| B symptoms (+) | 0.054 | 1.903 (0.989–3.659) | 0.575 | 1.580 (0.319–7.836) |
| Hemoglobin <12 | 0.146 | 1.553 (0.857–2.814) | 0.148 | 3.273 (0.656–16.345) |
| ALC <1.0 × 109/L | 0.355 | 1.359 (0.709–2.604) | 0.273 | 2.267 (0.525–9.800) |
| LN involvement (+) | 0.015 | 2.693 (1.212–5.981) | 0.263 | 32.070 (0.074–13925) |
| Multiple MALT organs (+) | 0.055 | 1.746 (0.987–3.088) | 0.642 | 0.745 (0.216–2.577) |
| BM (+) | 0.929 | 1.025 (0.599–1.751) | 0.848 | 1.132 (0.319–4.015) |
| Liver (+) | 0.105 | 0.423 (0.149–1.198) | 0.378 | 0.035 (0.000–60.303) |
| Chemotherapy (+) | 0.455 | 1.477 (0.531–4.112) | 0.511 | 23.6 (0.002–290466) |
*P‐value by Cox regression analysis. Bold values denote statistical significance. ALC, absolute lymphocyte count; BM, bone marrow; LDH, lactic dehydrogenase; LN, lymph node; MALT, mucosa‐associated lymphoid tissue; OS, overall survival; PS (ECOG), Eastern Cooperative Oncology Group Performance Status; TTP, time to progression; (+), yes.