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IC50values of pemetrexed in PC‐6, PC‐6/MTA‐0.4, PC‐6/MTA‐1.6, and PC‐6/MTA‐4.0 cells
| Cell lines | Pemetrexed IC50 (μm) | 95% CI (μm) | RR |
|---|---|---|---|
| PC6 | 0.1 | 0.07–0.13 | – |
| PC6/MTA‐0.4 | 0.53 | 0.32–0.88 | 5.3 |
| PC6/MTA‐1.6 | 2.38 | 1.51–3.76 | 23.8 |
| PC6/MTA‐4.0 | 43.87 | 22.08–87.20 | 438.7 |
RR, resistance rate: (IC50 in resistant subline)/(IC50 in the parental subline).
