Table 2.
Significant prognostic factors by univariate and multivariate analysis (Cox’s proportional hazards model)
| Variable | Hazard ratio (95% CI) | P‐values |
|---|---|---|
| Univariate analysis | ||
| Histologic grade (Well/Mod/Poor) | 2.386 (1.283–4.438) | 0.006 |
| LN metastasis (N0/N1 + N2) | 5.300 (2.527–11.113) | 0.000 |
| Distant metastasis (M0/M1) | 13.303 (6.909–25.625) | 0.000 |
| TNM stage (I + II/III + IV) | 3.685 (2.068–6.568) | 0.000 |
| TAGLN2 expression (Low/Moderate/High) | 2.866 (1.921–4.275) | 0.000 |
| Multivariate analysis | ||
| LN metastasis | 2.794 (1.246–6.263) | 0.012 |
| Distant metastasis | 8.318 (4.119–16.798) | 0.000 |
| TAGLN2 expression | 1.639 (1.018–2.638) | 0.042 |
CI, confidence interval; LN, lymph node; TAGLN2, transgelin‐2.