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. 2009 Oct 10;101(2):550–558. doi: 10.1111/j.1349-7006.2009.01390.x

Figure 1.

Figure 1

 Expression of 15‐hydroxyprostaglandin dehydrogenase (15‐PGDH) and cyclooxygenase‐2 (COX‐2) protein in gastric adenocarcinoma. (a,b) In noncancerous gastric epithelial cells, immunoreactivity for 15‐PGDH protein was observed mainly in the cytoplasm of epithelial cells and inflammatory cells in the lamina propria. (c,d) In case immunoreactivity for 15‐PGDH was observed in tumor tissue, 15‐PGDH protein was also observed in cytoplasm in cancer cells. (e,f) Immunoreactivity for 15‐PGDH protein was very weak in some cancer tissues. (a, c, e) H&E staining; (b, d, f) immunostaining for 15‐PGDH. N, noncancerous epithelium; T, tumor tissue. (g) COX‐2 protein was observed in cancer cells. (h) Immunoreactivity for COX‐2 protein was very weak in some cancer tissues (original magnification, ×200).