Table 3.
p53 mutation status
| Case | Codon change | Amino acid change | Exon | Case | Codon change | Amino acid change | Exon |
|---|---|---|---|---|---|---|---|
| 1 | – | 37 | 72. 2‐bp deletion | Frameshift | 4 | ||
| 2 | 306.CGA/TGA | Arg/Early stop | 8 | 38 | – | ||
| 3 | ND | 39 | – | ||||
| 4 | 168. ‐AG‐insert | Early stop | 5 | 40 | – | ||
| 5 | – | 41 | – | ||||
| 6 | 193.CAT/CTT | His/Leu | 6 | 42 | 173.GTG/ATG | Val/Met | 5 |
| 7 | – | 43 | – | ||||
| 8 | – | 44 | – | ||||
| 9 | – | 45 | 207. 1‐bp deletion | Frameshift | 7 | ||
| 10 | – | 46 | – | ||||
| 11 | – | 47 | – | ||||
| 12 | ND | 48 | 155.ACC/GCC, 213.CGA/TGA | Thr/Ala, Arg/Early stop | 5, 6 | ||
| 13 | – | 49 | – | ||||
| 14 | – | 50 | 191.CCT/CGT | Pro/Arg | 6 | ||
| 15 | Deletion | Frameshift | 7 | 51 | – | ||
| 16 | – | 52 | – | ||||
| 17 | – | 53 | – | ||||
| 18 | – | 54 | 175. CGC/CAC | Arg/His | 5 | ||
| 19 | – | 55 | – | ||||
| 20 | 193.CAT/CTT | His/Leu | 6 | 56 | – | ||
| 21 | – | 57 | – | ||||
| 22 | – | 58 | 237.ATG/ATA | Met/Ile | 7 | ||
| 23 | 502. 2 bp insert | Frameshift | 5 | 59 | – | ||
| 24 | – | 60 | 220.TAT/TGT | Tyr/Cys | 7 | ||
| 25 | – | 61 | 192.CAG/TAG | Gln/Early stop | 6 | ||
| 26 | 278.CCT/CTT | Pro/Leu | 8 | 62 | Splice junction | Int8‐Ex9 junction AG‐AT | 9 |
| 27 | – | 63 | – | ||||
| 28 | 192.Del & Ins | Frameshift | 6 | 64 | – | ||
| 29 | 175.CGC/CAC | Arg/His | 5 | 65 | 151.CCC/CGC | Pro/Arg | 5 |
| 30 | 278.CCT/TCT | Pro/Ser | 8 | 66 | – | ||
| 31 | – | 67 | 244.GGC/GTC | Gly/Val | 7 | ||
| 32 | 220.TAT/TGT | Tyr/Cys | 6 | 68 | – | ||
| 33 | 245.GGC/AGC | Gly/Ser | 7 | 69 | 220.TAT/AAT | Tyr/Asn | 6 |
| 34 | 135. ‐A‐insert | Early stop | 5 | 70 | – | ||
| 35 | 179.CAT/TAT | His/Tyr | 5 | 71 | 179.CAT/CGT | His/Arg | 5 |
| 36 | – |
Del, deletion; Ins, insertion; ND, not done.