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Table 2.

Immunohistochemical nuclear expression of S100A4 in epithelial ovarian neoplasms

Total number of cases Nuclear staining
+ + +
Benign cystadenomas 24 24(100%)  0(0%)  0(0%)
 Serous  4  4  0  0
 Mucinous 20 20  0  0
Borderline tumors 20 17(85%)  0(0%)  3(15%)
 Serous  8  6  0  2
 Mucinous 12 11  0  1
Carcinomas 69 34(49%) 18(26%) 17(25%)
FIGO stage
 I 33 20  8  5
 II 10  5  2  3
 III 21  6  8  7
 IV  5  3  0  2
Histological type
 Serous 25 11  6  8
 Mucinous  5  1  3  1
 Endometrioid 17  9  4  4
 Clear cell 22 13  5  4
Histological grade
 G1 31 17  7  7
 G2 27 13  8  6
 G3 11  4  3  4

–, 0–10% positive cells; +, 10–20% positive cells; + +, more than 20% positive cells.