Table 1.

 Inhibition of hepatic metastasis of LS‐LM6 cells by si‐RNA

si‐RNA	Hepatic metastasis			Weight of spleen‡ (mg)
	Incidence†	Number of nodules‡	Tumor volume§
si‐control	8/8	100.7 ± 54.7**	125.6 ± 106*	283 ± 66
si‐integrin αv	8/8	14.9 ± 11.4**	15.6 ± 12*	233 ± 44.7
si‐erbB3	8/8	11.3 ± 11.7**	11.7 ± 12.2*	214 ± 65.9

*P < 0.05; **P < 0.01. †Number of mice with hepatic metastasis/number of mice which received splenic injection. ‡Average ± SD. §Tumor volume was calculated by (diameter of nodules/2)³ × 4π/3 and summed for each nodule, average ± SD.