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. 2007 Sep 28;98(12):1868–1874. doi: 10.1111/j.1349-7006.2007.00621.x

Figure 4.

Figure 4

Effects of overexpression of the phosphomimic or unphosphorylated mutants of retinoid X receptor (RXR) α on retinoic acid receptor responsive element (RARE) promoter activity in 293T cells. The 293T cells were cotransfected with wild‐type or mutant RXRα‐expressing plasmids (T82A/S260A or T82D/S260D) using the RARE‐Luc and CMV‐Luc plasmids. The transfected cells were then treated with vehicle or 1.0 µM 9‐cis‐retinoic acid for 24 h and the extracts were examined for luciferase activity. Values are the mean ± SD. Asterisks represent significant differences (P < 0.05). Representative results from three independent experiments are shown.