Table 2.
Expression pattern of C4.4A and clinicopathological parameters in colorectal cancer patients with stage I–IV tumors (n = 132)
| A (n = 34) | B1, B2, C (n = 98) | P‐value | |
|---|---|---|---|
| Age in years, mean (range) | 61.5 (39–85) | 62 (40–93) | NS |
| Sex | |||
| Male | 22 | 59 | NS |
| Female | 12 | 39 | |
| Tumor size (cm), mean (range) | 5 (1.8–9) | 4.5 (1.1–17) | NS |
| Differentiation | |||
| Well, mod | 34 | 88 | NS |
| Por, muc | 0 | 10 | |
| Depth of invasion | |||
| ∼mp | 3 | 26 | 0.033 |
| ss∼ | 31 | 72 | |
| Lymph node metastasis | |||
| Negative | 14 | 55 | NS |
| Positive | 20 | 43 | |
| Venous invasion | |||
| Negative | 16 | 73 | 0.003 |
| Positive | 18 | 25 | |
| Distant metastasis | |||
| Negative | 27 | 82 | NS |
| Positive | 7 | 16 | |
| Liver metastasis | |||
| Negative | 27 | 85 | NS |
| Positive | 7 | 13 | |
| Lung metastasis | |||
| Negative | 32 | 94 | NS |
| Positive | 2 | 4 | |
| Peritoneal dissemination | |||
| Negative | 34 | 90 | NS |
| Positive | 0 | 8 | |
| Stage | |||
| I, II | 12 | 52 | NS |
| III, IV | 22 | 46 | |
Colorectal cancer cases (n = 132) were categorized as: (A) translocation from cytoplasm to membrane and with enhanced intensity (n = 34); (B1) translocation but without enhanced intensity (n = 12); (B2) no translocation but with enhanced intensity (n = 15); or (C) no translocation and without enhanced intensity (n = 71). mp, muscularis propria; NS, not significant; Por, muc, poorly differentiated adenocarcinoma or mucinous carcinoma; ss, subserosa; Well, mod, well or moderately differentiated adenocarcinoma.