Table 3.
Expression pattern of C4.4A and clinicopathological parameters in colorectal cancer patients with stage II and III tumors (n = 82)
| A (n = 34) | B1, B2, C (n = 98) | P‐value | |
|---|---|---|---|
| Age in years, mean (range) | 64 (39–85) | 62 (47–79) | NS |
| Sex | |||
| Male | 14 | 36 | NS |
| Female | 11 | 21 | |
| Tumor size (cm), mean (range) | 5 (1.8–9) | 5 (1.4–17) | NS |
| Differentiation | |||
| Well, mod | 25 | 52 | NS |
| Por, muc | 0 | 5 | |
| Depth of invasion | |||
| ∼mp | 2 | 6 | NS |
| ss∼ | 23 | 51 | |
| Lymph node metastasis | |||
| Negative | 11 | 33 | NS |
| Positive | 14 | 24 | |
| Venous invasion | |||
| Negative | 12 | 46 | 0.003 |
| Positive | 13 | 11 | |
Colorectal cancer cases were categorized as: (A) translocation from cytoplasm to membrane and with enhanced intensity; (B1) translocation but without enhanced intensity; (B2) no translocation but with enhanced intensity; or (C) no translocation and without enhanced intensity. mp, muscularis propria; NS, not significant; Por, muc, poorly differentiated adenocarcinoma or mucinous carcinoma; ss, subserosa; Well, mod, well or moderately differentiated adenocarcinoma.