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Figure 1.

Figure 1

(A) Time to response (TTR) and (B) time to complete response (TTCR). Medians were estimated by the Kaplan‐Meier method. A total of 63 patients (Arm C [‐], 30; Arm S [‐‐‐], 33) were analyzed for TTR, and 44 patients (Arm C, 21; Arm S, 23) for TTCR with per protocol sets of data. Median TTRs in Arm C and Arm S were 61 days (95% confidence interval [CI] 59 to 65 days) and 62 days (95% CI 60–70 days), respectively. The 75th percentile TTRs in Arm C and Arm S were 66 days (95% CI 63 to 76 days) and 140 days (95% CI 66–135 days), respectively (P = 0.0994, log–rank test). Median TTCRs in Arm C and Arm S were 136 days (95% CI 65 to 213 days) and 140 days (95% CI 134–227 days), respectively. The 75th percentile TTCRs in Arm C and Arm S were 228 days (95% CI 141 to 293 days) and 295 days (95% CI 153–323 days), respectively (P = 0.2201, log–rank test).