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IC50 value in various EGFR‐overexpressing cancer cell lines
| Compound | IC50 (μM) | |||||
|---|---|---|---|---|---|---|
| A549 | SK‐OV‐3 | HCT15 | A431 | MDA‐MB‐231 | SK‐BR‐3 | |
| KO‐202125 | 1.0 | 1.3 | 1.4 | 1.15 | 1.17 | 1.79 |
| Gefitinib | 7.5 | 1.8 | 5.9 | 1.46 | 13.36 | 0.93 |
A431, skin cancer; A549, lung cancer; EGFR, epidermal growth factor receptor; HCT15, colorectal cancer; MDA‐MB‐231 and SK‐BR‐3, breast cancer; SK‐OV‐3, ovarian cancer.
