Table 3.
Relationship between LC3 expression and clinicopathological factors of pancreatic cancer
| No. cases | LC3 expression | P‐value | |||
|---|---|---|---|---|---|
| N | W | S | |||
| Age | |||||
| <65 years | 37 | 3 | 10 | 24 | |
| ≥65 years | 34 | 6 | 13 | 15 | 0.1875 |
| Sex | |||||
| Male | 40 | 5 | 13 | 22 | |
| Female | 31 | 4 | 10 | 17 | 0.9987 |
| Tumor size | |||||
| <3.0 cm | 34 | 3 | 17 | 14 | |
| ≥3.0 cm | 37 | 6 | 6 | 25 | 0.0098 |
| Predominant differentiation | |||||
| Well | 25 | 5 | 13 | 7 | |
| Moderately | 37 | 3 | 8 | 26 | 0.0227 |
| Poorly | 9 | 1 | 2 | 6 | |
| Lowest differentiation | |||||
| Well | 8 | 2 | 5 | 1 | |
| Moderately | 27 | 2 | 11 | 14 | 0.0431 |
| Poorly | 36 | 5 | 7 | 24 | |
| Lymphatic vessel infiltration | |||||
| 0 or 1 | 50 | 6 | 19 | 25 | |
| 2 or 3 | 21 | 3 | 4 | 14 | 0.2940 |
| Blood vessel infiltration | |||||
| 0 or 1 | 7 | 1 | 5 | 1 | |
| 2 or 3 | 64 | 8 | 18 | 38 | 0.0497 |
| Intrapancreatic neural invasion | |||||
| 0 or 1 | 20 | 3 | 6 | 11 | |
| 2 or 3 | 51 | 6 | 17 | 28 | 0.1680 |
| Retroperitoneal invasion | |||||
| 0 or 1 | 27 | 4 | 12 | 11 | |
| 2 or 3 | 44 | 5 | 11 | 28 | 0.1567 |
| UICC pT | |||||
| pT1 or pT2 | 4 | 1 | 1 | 2 | |
| pT3 | 67 | 8 | 22 | 37 | 0.7415 |
| UICC pN | |||||
| pN0 | 11 | 2 | 5 | 4 | |
| pN1 | 60 | 7 | 18 | 35 | 0.4038 |
| UICC pStage | |||||
| IA/IB/IIA | 14 | 2 | 6 | 6 | |
| IIB/III/IV | 57 | 7 | 17 | 33 | 0.5805 |
| Tumor necrosis | |||||
| Absent | 50 | 7 | 21 | 22 | |
| Present | 21 | 2 | 2 | 17 | 0.0127 |
| Nerve plexus invasion | |||||
| Absent | 26 | 3 | 9 | 14 | |
| Present | 45 | 6 | 14 | 25 | 0.9450 |
N, negative; S, strongly positive; W, weakly positive.