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Tamoxifen (TAM) derivatives induced cell damage to estrogen receptor (ER)‐positive and ‐negative cells. (a) ER‐positive HL‐60 cells or (b) ER‐negative Jurkat cells were incubated with the indicated doses of TAM derivatives for 4 h. (c) Jurkat cells were incubated with the indicated doses of ridaifen (RID)‐B for 48 h. Cell viability was estimated by WST‐8 assay. Each bar denotes the standard deviation (n = 3).
