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Treatment with oxaliplatin (L‐OHP) combined with 5‐fluorouracil (5FU) prolongs survival in mice with implanted TU‐OM‐1 cells. Female nude mice (five per group) were given an intraperitoneal (i.p.) injection of 2 × 106 TU‐OM‐1 cells followed by weekly i.p. injections of 250 µL PBS, 12.5 mg/kg L‐OHP, and/or 25 mg/kg 5FU for 3 weeks (days 5, 12, 19). Treatment with L‐OHP and 5FU prolonged survival relative to treatment with PBS, L‐OHP or 5FU (P < 0.005).
