Table 3.
CYP7A1 A‐203C polymorphism and risk of colorectal adenoma by location
Genotype | Proximal colon | Distal colon | Rectum | |||
---|---|---|---|---|---|---|
n † | OR (95% CI) ‡ | n † | OR (95% CI) ‡ | n † | OR (95% CI) ‡ | |
AA | 44/219 | 1.00 (referent) | 42/219 | 1.00 (referent) | 10/219 | 1.00 (referent) |
AC | 73/452 | 0.82 (0.54–1.24) | 86/452 | 1.01 (0.67–1.52) | 23/452 | 1.07 (0.49–2.35) |
CC | 29/243 | 0.56 (0.34–0.95) | 52/243 | 1.14 (0.72–1.80) | 9/243 | 0.89 (0.35–2.31) |
Numbers of cases/controls.
‡ Adjusted for age, hospital, rank, body mass index, cigarette smoking, alcohol use, physical activity and parental history of colorectal cancer. CI, confidence interval; OR, odds ratio.