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Table 3.

CYP7A1 A‐203C polymorphism and risk of colorectal adenoma by location

Genotype Proximal colon Distal colon Rectum
n OR (95% CI) n OR (95% CI) n OR (95% CI)
AA 44/219 1.00 (referent) 42/219 1.00 (referent) 10/219 1.00 (referent)
AC 73/452 0.82 (0.54–1.24) 86/452 1.01 (0.67–1.52) 23/452 1.07 (0.49–2.35)
CC 29/243 0.56 (0.34–0.95) 52/243 1.14 (0.72–1.80) 9/243 0.89 (0.35–2.31)

Numbers of cases/controls.

Adjusted for age, hospital, rank, body mass index, cigarette smoking, alcohol use, physical activity and parental history of colorectal cancer. CI, confidence interval; OR, odds ratio.