Table 2.

 Univariate and multivariate Cox regression analyses of gastric cancer‐specific survival in 225 gastric cancer patients

	Comparison/referent	Univariate			Multivariate
		HR	95% CI	P	HR	95% CI	P
Age	≥60/<60	1.745	0.978–3.115	0.060			NS
Gender	Female/male	1.282	0.679–2.136	0.341
Histological type	Undiff./diff.	0.961	0.587–1.572	0.837
Depth of invasion	T3–4/T1–2	2.019	1.697–2.404	<0.001	1.307	1.039–1.644	0.022
Lymph node metastasis	Present/absent	10.836	4.670–25.145	<0.001	3.551	1.300–9.703	0.013
Distant metastasis	Present/absent	14.014	7.674–25.595	<0.001	3.555	1.876–6.736	<0.001
TNM stage	III–IV/I–II	2.226	1.832–2.705	<0.001	1.392	1.037–1.868	0.028
MECA‐79 expression	Positive/negative	2.856	1.744–4.678	<0.001	2.034	1.202–3.444	0.008

CI, confidence interval; diff., differentiated; HR, hazard ratio; NS, not significant; undiff., undifferentiated.