Figure 6.

Growth inhibition of subcutaneous tumor by the treatment with adiponectin. AZ521 (1 × 10⁶ in 100 µL phosphate‐buffered saline [PBS]) were subcutaneously implanted in nude mice. Adiponectin (5 µg or 50 µg per mouse) dissolved in 100 µL of PBS or PBS alone were intratumorally injected every day from 3 days after tumor inoculation throughout the experiment. Dots and bars indicate mean and SD in five mice treated with high or low concentrations of adiponectin and PBS in a representative one in three different sets of experiments.