Figure 3.

Fragile structure of (a) blood vessel and (c) peritoneal membrane in calponin (CN)‐deficient mice.^{( 50 )} Augmentation of (b) blood‐born metastasis and (d) peritoneal dissemmination of B16‐F10 cells in calponin‐deficient mice.^{( 50 )} (a) Top: Electronmicroscopic image of lung arterioles. The walls of the vessels are thinner in the calponin‐deficient mice than in the normal mice. Scale bar = 5 µm. (a) Bottom: Scanning electronmicroscopic image of the surface of lung capillaries. The capillaries of the calponin‐deficient mice have an irregular surface. Scale bar = 100 nm.