Figure 6.

(a,b) Viability of UV‐exposed or (c,d) cisplatin‐treated (a,c) NB1RGB (normal) or (b,d) HeLa cells (effects of MG‐262 or caffeine.) UV‐exposed cells were cultured for 5 h in a normal medium containing 3.0 mM caffeine (closed circle) or 0.33 µM MG‐262 (closed triangle) or without either (open circle). They were rinsed with phosphate‐buffered saline (PBS) and cultured in the normal medium for 1 day. Then, 200 µL of resazurin solution was added to the medium and the cells were incubated for a further 1 h. The medium was recovered, and the resorufin fluorescence was measured. Cisplatin treatment was performed by incubating the cells in a normal medium containing various doses of cisplatin for 1 h, instead of UV. Points, the means of three independent experiments; bars, SE.