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. 2008 Oct 9;99(10):1892–1900. doi: 10.1111/j.1349-7006.2008.00904.x

Figure 6.

Figure 6

Effect of the peroxisome proliferator‐activated receptor γ (PPARγ) inhibitor T0070907 on the activity of Rac‐1 and Cdc42 GTPases in Capan‐1 cells. GTPase activity for Rac‐1 and Cdc42 was measured using GST pull‐down assays that are capable of distinguishing the percentage of the active fraction (relative to total) of Rac‐1 and Cdc42 in lysates of Capan‐1 cells. Treatment with T0070907 (0.1 and 1.0 µmol/L) resulted in a significant decrease in the percentage of active Rac‐1 and Cdc42. Each column represents the mean ± SD. The experiments were carried out six times. *P < 0.05.