. 2008 May 12;99(7):1492–1498. doi: 10.1111/j.1349-7006.2008.00837.x

Table 6.

Urinary excretion of sorafenib and metabolites 48 h after single administration of sorafenib

Dose (mg bid)	Sorafaneib (BAY 43‐9006) (%)	M‐2 (BAY 67‐3472) (%)	M‐7 (BAY 43‐9006G) (%)	M‐8 (BAY 67‐3472G) (%)
100	ND	ND	4.15 (34) ^†	0.09 (0) ^‡
200	ND	ND	1.97 (55) ^§	0.08 (99) ^¶
400	ND	ND	1.66 (64) ^††	0.11 (99) ^‡‡
600	ND	ND	1.70 (66) ^††	0.09 (120) ^††

Percent coefficient of variance is expressed in parentheses.

BAY 43‐9006G: BAY 43‐9006 glucuronide, BAY 67‐3472G: BAY 67‐3472 glucuronide.

^{^†}

n = 3,

^{^‡}

n = 2,

^{^§}

n = 2,

^{^¶}

n = 9,

^{^††}

n = 5,

^{^‡‡}

n = 4.

ND, not detected.