TABLE 3.
Tissue | PrV-9112C2R
|
PrV-9112C2
|
||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1b | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
Regio cutanea | + | ++++ | +++ | ++++ | + | + | ||||||||||
Regio respiratoria | ++ | +++ | ++ | +++ | ++ | +++ | + | +++ | ||||||||
Regio olfactoria | ++++ | + | + | ++++ | + | + | ++++ | ++++ | +++ | +++ | ++ | |||||
Ganglion trigeminale | ++++ | +++ | ++ | + | + | + | + | + | ||||||||
Bulbus olfactorius | ++ | +++ | ++ | +++ | +++ | ++++ | ++ | + | ||||||||
Pedunculus olfactorius | + | ++ | + | +++ | ++++ | ++ | + | |||||||||
Pons | + | ++ | ++ | + | ||||||||||||
Medulla oblongata | + | + | ++ | + | ++ | + | ||||||||||
Mesencephalon | + | + | + | |||||||||||||
Diencephalon | + | ++ | + | |||||||||||||
Cerebrum | ++ | |||||||||||||||
Cerebellum | + | ++ | +++ | |||||||||||||
Tonsil | + | ++ | + |
Evaluation: +, <50 cells in nasal mucosa and tonsils, <10 nerve fibers and/or 5 perikarya in trigeminal ganglion, <25 large perikarya and/or <5 plaques with <30 small perikarya in brain; ++, <150 cells in nasal mucosa and tonsils, <50 nerve fibers and/or 10 perikarya in trigeminal ganglion, <200 large perikarya and/or <20 plaques with <30 small perikarya in brain; +++, <300 cells in nasal mucosa and tonsils, <100 nerve fibers and/or 20 perikarya in trigeminal ganglion, <500 large perikarya and/or <50 plaques with <30 small perikarya in brain; ++++, >300 cells in nasal mucosa and tonsils, >100 nerve fibers and/or 50 perikarya in trigeminal ganglion, >500 large perikarya and/or >50 plaques with <30 small perikarya in brain.
Day p.i.