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. 2024 Jun 7;10(23):eadj3194. doi: 10.1126/sciadv.adj3194

Fig. 3. IKKβ overexpression up-regulates inflammatory cytokine, chemokine, catabolic enzyme, and neurotrophic factor gene expression.

Fig. 3.

Gene expression changes (relative to control) from total RNA isolated from control (AcanCre−/−;Ikk2cafl/fl) and IKKβCA whole caudal and lumbar IVDs containing NP, AF, and EP, 1 week after recombination. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 (n = 3 mice per genotype, one IVD per mouse).