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Genetic organization and expression of Friend murine leukemia virus (Fr-MLV). (A) Fr-MLV provirus. LTR, long terminal repeat. (B) Viral RNAs: full-length viral RNA (used as genomic RNA, pre-mRNA, and mRNA) and splice RNA (used as messenger for env). SD, splice donor site; SA, splice acceptor site; E/DLS, dimerization and encapsidation sequence; Poly A, polyadenylate sequence. The numbering is with respect to the 5′ cap (+1).
