Figure 4: In-silico experimentation enables precise investigation of the epistatic interactions between initiation motifs.

The measured PRO-cap data and original ProCapNet prediction and contribution scores (profile task) at the primary MYC promoter are shown, followed by the model prediction and scores generated from sequences with a single sequence feature modified from the original sequence (indicated by the black boxes). All model predictions, and all downscore tracks, are plotted on the same y-axis scales.