Figure 3:

Evolutionary dynamics of disease resistance, using the discrete random loci model A: Phenotypic changes in resistance over the course of a simulation with no epistasis. B: Distribution of host genotypes with genotypes that had large populations at some point in evolutionary time in orange. Blue dots represent genotypes present at the end of the simulation, while orange dots are genotypes that were present at previous ecological equilibrium but not the final equilibrium. Panels A and B correspond to the same simulation. C: Equilibrium genetic diversity across simulations with 100 different allelic instantiations for each epistasis treatment. There was no significant difference in the Shannon diversity across treatments. Parameters: ${\beta }_0=0.005,$ $\mu =0.2,$ $\gamma =0.001$, the parameters for the trait distributions are the same as in Fig. 2.