Figure 2. Pdcd10^BECKO mice display behavioral deficits linked to an increase in CCM lesion burden.

Histological analysis of brain sections from P35, P38, and P42 Pdcd10^ECKO mice. Multiple CCM lesions were detected in sections stained with hematoxylin and eosin (Pink) at the hippocampal brain region. The arrowhead indicates CCM lesions, while the arrows show intra and extra-lesional bleeding present in P42 Pdcd10^BECKO brains. Scale bars are 500 μm and 50 μm for high magnification.