Table 6: Notable putative auxiliary metabolic genes encoded by viruses in the landfill datasets.
Entries marked with an * represent functions also observed in 100k randomly selected IMG/VR prokaryotic viruses, but which are not widely reported in the literature. Functions are presented in alphabetical order according to AMG name. Highest confidence AMGs are marked with an ^ and explored further with phylogenetic trees.
| AMG name | Sites: # instances per site | AMG function |
|---|---|---|
| aprB; adenylylsulfate reductase, subunit B [EC:1.8.99.2] | SO_2017: 1 | Sulfur metabolism |
| dehH; haloacetate dehalogenase [EC:3.8.1.3] | CA:1 | Chlorocyclohexane and chlorobenzene degradation, Chloroalkane and chloroalkene degradation |
| Ê3.2.1.1A; alpha-amylase [EC:3.2.1.1] | NEUS: 1 | Polysaccharide metabolism |
| ^frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1] | SO_2016: 1 SO_2017: 8 |
Methane metabolism, Redox reactions (e.g., hydrogen oxidation) |
| hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] / 4Fe-4S binding domain | NEUS: 1 SO_2017: 1 |
Methanogenesis |
| mcrD; methyl-coenzyme M reductase subunit D | CA:1 | Methanogenesis, anaerobic methane metabolism |
| mddA; methanethiol S-methyltransferase [EC:2.1.1.334] | CA:1, SO_2017:1 |
Methionine metabolism to dimethyl sulfide |
| *phoD; alkaline phosphatase D [EC:3.1.3.1] | CA:3 NEUS:1 |
Alkaline phosphatase |
| *^rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39] | NEUS:1 SO_2016:1 SO_2017:3 |
D-ribulose 1,5-bisphosphate carboxylation, carbon dioxide fixation |
| soxX; L-cysteine S-thiosulfotransferase [EC:2.8.5.2] | CA:1 | Thiosulfate oxidation |