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. Author manuscript; available in PMC: 2024 Jun 7.
Published in final edited form as: Cancer Res. 2020 Jan 27;80(8):1656–1668. doi: 10.1158/0008-5472.CAN-19-1704

Fig. 2. BAP1 deficiency cooperates with KrasG12D to cause invasive pancreatic adenocarcinoma.

Fig. 2.

(A) Generation of pancreas specific deletion of BAP1 (Pdx1.cre).

(B) Haematoxylin and eosin staining of pancreas from 8 week old mice of different genotypes. Bar = 100 μM

(C) Percentage incidence of pancreatic lesions seen in mice of indicated genotypes.

(D) Carboxypeptidase A (CPA1), keratin (K19) and Ki-67 immunohistochemistrty (IHC) of pancreas from 8 week old mice of indicated genotypes. Bar = 50 μM

All data are representative images for at least 5 mice of each genotype.