FIG 2.

Prevalence counts irAEs from structured diagnosis codes and AC of clinical notes. (A) Comparison of patient counts found by AC model and structured diagnosis codes. (B) Patient counts found by AC models that were not found by structured diagnosis codes (structured diagnosis code FNs). In the absence of information from unstructured data, structured diagnosis codes capture a lot of noise and significantly over-estimate the prevalence of ICI-induced irAEs. AC, augmented curation; FNs, false negatives; ICI, immune checkpoint inhibitor; irAE, immune-related adverse event; SCAR, severe cutaneous adverse reaction.