Table 5.

Ruxolitinib administration in patients <12 years.

Weight, number (%)	NA in 30
<25 kg	51 (65)
>25 kg	27 (35)
Daily dose, mg/die, number (%)	NA in 30
• median (range)	10 mg (2.5–20)
• Starting dose in patients <25 kg (51 pts),
○ 10 mg/die	19 (37)
○ 5 mg/die	24 (47)
○ 2.5 mg/die	5 (10)
○ 20 mg/die	3 (6)
• Starting dose in patients >25 kg (27 pts)
○ 10 mg/die	22 (81)
○ 20 mg/die	5 (19)
• Maximum dose reached
• 20 mg/die	• 16 (21)
• 15 mg/die	• 7 (9)
• 10 mg/die	• 37 (47)
• 5 mg/die	• 18 (23)
Total treatment time, days, median (range)	80 (1–610) (NA in 3 patients)