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. 2024 Apr 22;28(6):2131–2147. doi: 10.1007/s10461-024-04311-4

Table 14.

Post-hoc analysis: multi-variate model including an interaction between time period and being hospitalised for an injecting-related admission in the last 2 years among people prescribed OAT in all of Glasgow, 2010–2021 (June 2021 only)

Co-variates Na HIV test in the last year (% of N) Multi-variateb
aOR (95% CI) P value
Injecting-related hospital admission in the last 2 years—NO
 Time perioda
  Pre-outbreak (2010–2014) 10,354 1,532 (15%) 0.16 (0.15–0.17)  < 0.001
  Early outbreak (2015–2016) 7,819 2,560 (33%) 0.48 (0.45–0.51)  < 0.001
  Ongoing outbreak (2017–2019) 7,359 3,613 (49%) 1
  COVID-19 (2020–2021) 5,829 1,804 (31%) 0.47 (0.44–0.51)  < 0.001
Injecting-related hospital admission in the last 2 years—YES
  Pre-outbreak (2010–2014) 1,554 411 (28%) 2.37 (2.09–2.67)  < 0.001
  Early outbreak (2015–2016) 1,700 870 (51%) 2.19 (1.97–2.44)  < 0.001
  Ongoing outbreak (2017–2019) 2,053 1440 (70%) 2.44 (2.19–2.71)  < 0.001
  COVID-19 (2020–2021) 1,770 1,043 (59%) 3.15 (2.81–3.51)  < 0.001
 Local authority area
  Rest of Glasgow 3,788 1,910 (50%) 1
  Glasgow city 10,410 6,198 (59%) 1.58 (1.49–1.68)  < 0.001
 Gender
  Male 9,783 5,659 (58%) 1
  Female 4,415 2,449 (55%) 0.91 (0.86–0.97) 0.002
 Age groupa
   < 35 6,738 2,312 (34%) 1
  35–45 17,801 5,960 (35%) 0.80 (0.75–0.86)  < 0.001
  46 +  14,619 5,031 (34%) 0.61 (0.56–0.65) 0.002

OR odds ratio, aOR adjusted odds ratio

aTime varying co-variate; people can be included in multiple categories

bMulti-level framework to adjust for across time period duplicates