Table 2.

Sample demographics and clinical characteristics

	Total (52)	CVID (31)	non-CVID (21)	OR/ MD	P value (univariate)
SAMPLE DEMOGRAPHICS
Male	21 (40%)	14 (45%)	7 (33%)	1.647	0.5653
Female	31 (60%)	17 (55%)	14 (67%)	0.6071	0.5653
Age	52.4 (48.0–56.8)	50.4 (44.1–56.7)	55.1 (48.9–61.4)	-4.7	0.3110
CLINICAL VARIABLES
Age at diagnosis	42.25 (36.9–47.6)	39.0 (32.3–45.8)	47.3 (38.4–56.1)	-8.2	0.1308
Disease duration	11.6 (8.0–15.2)	13.7 (8.8–18.5)	8.5 (2.8–14.1)	5.2	0.1481
Ig replacement therapy (IGRT)	32 (62%)	26 (84%)	6 (28%)	13.00	< 0.0001
IGRT duration	9.3 (5.5–13.1)	8.1 (4.8–11.4)	14.3 (-4.6–33.2)	-6.2	0.3474
Infections	42 (81%)	29 (94%)	13 (62%)	8.923	0.0045
Autoimmunity (AI)	34 (65%)	19 (61%)	15 (71%)	0.6333	0.4508
AI Cytopenia	10 (19%)	9 (29%)	1 (5%)	7.773	0.0348
Splenomegaly	13 (25%)	12 (39%)	1 (5%)	12.63	0.0055
Granulomatosis	9 (17%)	6 (19%)	3 (14%)	1.440	0.6354
Malignancies	11 (21%)	6 (19%)	5 (24%)	0.7680	0.6995
Lymphadenopathy	16 (31%)	12 (39%)	4 (19%)	2,684	0.1317
Lung involvement	16 (31%)	13 (42%)	3 (15%)	4.093	0.0430
Atopy	18 (35%)	10 (32%)	8 (38%)	0.7738	0.6642
Blood CMV replication	5 (10%)	5 (16%)	0 (0%)	Infinity	0.0529
Blood EBV replication	11 (21%)	6 (19%)	5 (24%)	0.7680	0.6995
Blood EBV/CMV replication	13 (25%)	8 (26%)	5 (24%)	1.113	0.8704

Quantitative variables are expressed as means with a 95% confidence interval, while qualitative variables are represented as absolute frequencies with percentages relative to the total of the respective column. P values were calculated by two-sided Fisher test for qualitative variables and by either unpaired two-tailed Student's t-test or Mann–Whitney u test for quantitative variables according to variable distribution and sample size. OR: odds ratio; MD: mean difference