Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jun 7;15:4874. doi: 10.1038/s41467-024-49031-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a UMAP plot is shown for cell type identification. Cell types are identified with expression patterns of well-known cell type markers. Each color represents a cell type. b UMAP plot shows the overall expression patterns of CIE LAB-associated genes. Each cell is colored according to the average scaled expression of CIE LAB values-associated genes. c Dot plot of gene expression in cell types and additional evidence of each gene from the GWAS. Genes in purple represent those in previously unreported loci. The color of the circular dot represents the scaled average expression of each gene across cell types and size of the circular dot represents the percentage of cells expressing each gene within a particular cell type. Rhombic dots in yellow, red, and blue represent genes containing nonsynonymous variants associated with skin color, genes colocalized in skin tissue, or tissues other than skin, respectively. Abbreviations: Keratinocytes Diff. differentiated keratinocytes, Keratinocytes Undiff. undifferentiated keratinocytes, EC endothelial cells.