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. 2024 May 28;121(23):e2322359121. doi: 10.1073/pnas.2322359121

Fig. 2.

Fig. 2.

CCDC6-RET fusion drives the Ras/MAPK signal pathway. (A) Live-cell imaging of TPC-1 cells with endogenous mClover-tagging of CCDC6-RET. (Scale bar, 10 μm.) (B) Western blotting upon expression of EV or CCDC6-RET-EGFP in TPC-1 cells. (C) Western blotting upon expression of EV or CCDC6-RET-EGFP in HEK293T cells. (D) Western blotting upon expression of EV or CCDC6-RET-EGFP in BEAS-2B cells. (E) Western blotting upon expression of CCDC6-RET-EGFP or RET-KD-EGFP in HEK293T cells. (F) Western blotting upon expression of CCDC6-101aa-EGFP or CCDC6-RET-EGFP in HEK293T cells.