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. 2024 Feb 28;245(1):70–83. doi: 10.1111/joa.14033

FIGURE 5.

FIGURE 5

Bicuspid aortic valve is seen in P7 Prkd1 em1/+ heart. (a) Axial view of a Prkd1 +/+ (WT) heart at P7 stage showing a normal aortic valve with three sinuses of the three leaflets. (b) A Prkd1 em1/+ (Het) heart with a bicuspid aortic valve (AV), with two sinuses from the two leaflets (right and left) denoted by an asterisk (bisinuate and bileaflet). The mitral valve (MV) is also denoted, with normal appearing anterior (A) and posterior (P) leaflets. (b′) Inset in b is taken at a slightly different angle to show the right and left coronary ostia are patent (open arrows). R, right; L, left; NC, non‐coronary; Ao, aorta; LA, left atrium; LV, left ventricle; RA, right atrium; RV, right ventricle; WT, wild type.