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. 2024 Apr 18;7(4):e248121. doi: 10.1001/jamanetworkopen.2024.8121

Table 4. Summary of Significant Diffusion Metrics Regions-of-Interest (ROIs) Associated With Neuropsychiatric Symptoms (Traumatic Brain Injury Only).

Model β (SE) t value P value LRT VIF R2 a
Fractional anisotropy of left UNC =  NSI cognitive + age + mean displacement
NSI cognitive 5.4 × 10−3 (1.9 × 10−3) 2.77 .003 57.9 1.06 0.195
Age 9.2 × 10−4 (1.1 × 10−3) 0.79 .21 36.9 1.08
Mean displacement −0.130 (0.046) −2.82 .003 103.5 1.10
ISOVF of genu CC = PCLC total + age + mean displacement
PCLC total 4.3 × 10−4 (1.9 × 10−4) 2.15 .01 48.3 1.01 0.079
Age 1.8 × 10−4 (4.6 × 10−4) −0.40 .35 11.4 1.06
Mean displacement −0.014 (0.018) −0.776 .21 17.4 1.07
ODI of left fornix/ST = PCLC-C + age + mean displacement
PCLC-C 1.2 × 10−3 (5.5 × 10−4) 2.09 .02 33.6 1.02 0.289
Age 1.9 × 10−3 (6.2 × 10−4) 3.06 .001 162.2 1.06
Mean displacement 0.55 (0.024) 2.26 .01 83.9 1.07

Abbreviations: CC, corpus callosum; ISOVF, isotropic volume fraction; LRT, likelihood ratio test; NSI, Neurobehavioral Symptom Inventory; PCLC, Posttraumatic Stress Disorder Checklist–Civilian version; ST, stria terminalis; UNC, uncinate fasciculus; VIF, variance inflation factor.

a

R2 calculated by 1 – (SS residual / SS total), where SS is the sum of the square.