Table 2.
Patient Characteristics Associated With Appeal of Self- or Partner/Friend/Family Member-Administered Long-acting Injectable Cabotegravir/Rilpivirine Among 3 Urban Human Immunodeficiency Virus Clinics in the United States (N = 370 Patients)a
| Characteristic | Appeal of Self-administered Injection | Appeal of Partner/Friend/Family Member-Administered Injection | ||
|---|---|---|---|---|
| Unadjusted OR (95% CI) |
Adjusted OR (95% CI) |
Unadjusted OR (95% CI) |
Adjusted OR (95% CI) |
|
| Age, y, χ2 (df) | 4.27 (2) | 7.41 (2)* | 0.53 (2) | 2.25 (2) |
| 18–29 | 1.03 (.59–1.78) | 1.28 (.69–2.38) | 1.20 (.69–2.07) | 1.60 (.86–3.01) |
| 30–49 | 1.49 (1.00–2.23)* | 1.86 (1.19–2.91)** | 1.12 (.75–1.67) | 1.22 (.77–1.92) |
| ≥50 | Ref. | Ref. | Ref. | Ref. |
| Race/ethnicity | ||||
| Non-Latinx White | 2.55 (1.53–4.25)*** | 2.09 (1.19–3.67)*** | b | 1.92 (1.11–3.32)* |
| Black/Latinx/Other | Ref. | Ref. | Ref. | Ref. |
| Gender | ||||
| Cisgender male | 1.02 (.69–1.51) | 96 (.60–1.55) | .87 (.59–1.29) | .77 (.47–1.26) |
| Cisgender female/gender minority | Ref. | Ref. | Ref. | Ref. |
| Sexual orientation | ||||
| Gay/bisexual/other | 1.71 (1.17–2.48)** | 1.81 (1.14–2.89)** | 1.35 (.93–1.97) | 1.37 (.88–2.22) |
| Heterosexual | Ref. | Ref. | Ref. | Ref. |
| Housing | ||||
| Stably housedc | 2.00 (1.35–2.96)*** | 2.17 (1.41–3.34)*** | 1.54 (1.04–2.28)* | 1.63 (1.05–2.54)* |
| Unstably housed or homeless | Ref. | Ref. | Ref. | Ref. |
| Opiate/stimulate use | ||||
| Past 30-d opiate/stimulant use | 0.93 (.58–1.48) | 0.77 (.49–1.20) | 1.13 (.71–1.80) | 0.92 (.53–1.62) |
| None | Ref. | Ref. | Ref. | Ref. |
| Engagement in care | ||||
| Well-engagedc | 1.34 (.89–2.03) | 1.31 (.83–2.05) | 1.26 (.83–1.91) | 1.20 (.76–1.89) |
| Less well-engaged | Ref. | Ref. | Ref. | Ref. |
| Health literacy | ||||
| Adequate | 1.55 (1.06–2.27)* | 1.31 (.87–1.97) | 1.24 (.85–1.83) | 1.10 (.72–1.67) |
| Inadequate | Ref. | Ref. | Ref. | Ref. |
| Site χ2 (df) | 2.43 (2) | 3.87 (2) | 5.45 (2) | 2.44 (2) |
| San Francisco | 1.43 (.91–2.25) | 1.67 (.95–2.05) | 1.70 (1.08–2.69)* | 1.76 (.99–3.10) |
| Atlanta | 1.18 (.74–1.90) | 1.54 (.92–2.56) | 1.24 (.77–2.00) | 1.32 (.79–2.21) |
| Chicago | Ref. | Ref. | Ref. | Ref. |
Abbreviations: CI, confidence interval; df, degrees of freedom; OR, odds ratio.
aN = 367 for all unadjusted analyses except for heterosexual (n = 364), substance use (n = 365), and health literacy (n = 356); n = 353 for adjusted analyses.
bPartial proportional odds results for this covariate are reported in this footnote given the violation of the proportional odds assumption: For extremely/not at all: OR, 1.76 (95% CI, .94–3.32); very/not at all: OR, 1.70 (95% CI, .87–2.99); moderately/not at all: OR, 3.50 (95% CI, 1.91–6.23)***; slightly/not at all: OR, 4.08 (95% CI, 2.00–8.34)***.
cStably housed: owning or renting; well-engaged in care: virally suppressed (HIV-1 RNA <200 copies/mL) or ≥2 primary care visits attended in prior 12 months.
*P ≤ .05.
**P≤ .01.
***P ≤ .001.